Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) represent different degrees of a severe, acute, life-threatening mucocutaneous reaction resulting mainly from drugs. Both are considered a medical emergency that requires hospitalization and management of patients is usually provided in intensive care units or burn centers.
By current convention, the following terminology is used: the term SJS is used when the disease involves less than 10% of the total body surface area; and the term TEN is used when the disease involves more than 30% of the body surface area. Medications are the major precipitating cause and no specific treatment modality has been proven effective.
Recovery can take weeks to months, and there are numerous long-term sequelae. The recovery journey may look different for each survivor: some are able to resume their normal duties example work, with some modifications, while others are unable to return to work or their normal duties. Many survivors may suffer from psychological complications and low health related quality of life, and require long-term medical follow up.
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